Persistent educational inequalities are obstacles to social cohesion, wellbeing and inclusive economic growth in the Global South. Ensuring access to education from an early age and promoting the completion of secondary school with quality learning is an obligation on states and key to our collective futures. Using data from Argentina, Brazil and India, this policy brief presents key strategies to overcome the prevailing inequalities, with examples from initiatives implemented in country-specific contexts. These examples offer lessons to scale up targeted interventions and support programmes for continued participation of at-risk children. These recommendations are aimed at leveraging initiatives and reducing equity gaps within, and beyond, G20 countries. The G20 provides a valuable platform for advocating effective policy interventions and advancing multilateral commitments to eliminate educational inequities.